The term “Physiology” is derived from a Greek root with a Latin equivalent “Physiologia” originally meaning “Natural knowledge”. Most of the Nobel Prizes in the medicine are awarded in the field of physiology. Physiology is the study of normal functions and functioning of different organs or organ systems present in the human body. William Harvey (1578- 1657) who laid the foundations of experimental physiology is considered as “the father of physiology”. His great discovery was blood circulation- blood travels round in a circuit, returning again and again to the same point. It describes the chemistry and Physics behind basic body functions. It helps us understand what happens in a healthy body in everyday life and what goes wrong when someone gets sick. The study of physiology is, in a sense, study of life. It asks questions about the internal workings of organism and how they interact with the world around them. The most relevant arm of physiological research to medical news today is applied human physiology; this field investigates biological systems at the level of the cell, organ and organ system. Hence explore and utilize the facts and principles in the field of physiology to application level in undergraduate, postgraduates and research level for the maximum benefit of human being.